Medicine That Helps You Pee – Frequent urination has several potential causes, one of which may be medications you are taking.
You may have noticed recently running to the bathroom. Or you have to get up in the middle of the night and go. You may need to take more breaks at work to urinate.
Medicine That Helps You Pee
There are many potential causes of frequent urination. As the Mayo Clinic points out, this includes increased fluid intake and the development of new diseases such as urinary tract infections or diabetes.
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The urge to leave is a relatively common side effect of many over-the-counter medications. “Many medications can cause ‘overflow incontinence’ and urinary retention, in which the bladder is unable to contract and effectively expels urine, leaving urine in the bladder,” says Brooke D. Hudspeth, associate professor at PharmD. She is Director of Practice at the University of Kentucky School of Pharmacy in Lexington. Other drugs may interfere with the function of the urethra, causing leaks or causing the bladder to fill up quickly, causing the person to urinate more often.
Whether you’re taking a diuretic (“water pill”) to lower your blood pressure, a decongestant to clear out your sinuses, or a mood stabilizer for bipolar disorder, here are some common medications that make you urinate more:
The goal of diuretics is to increase urination. “All diuretics work by increasing the excretion of water and sodium from the body through the kidneys,” explains Dr. Hudspeth. This helps treat conditions like high blood pressure, swelling, heart failure, and liver or kidney failure, he says. However, urinating more can interfere with sleep if you wake up several times to go to the bathroom. Hudspeth recommends asking your doctor if you can take a diuretic early in the morning to avoid disturbing your sleep.
Urination is usually a well-organized process. When the bladder is full (and contains urine), the urethra, the tube connected to the bladder through which urine is emptied, should be closed to keep everything in place until you decide you’re ready to go, says Hudspeth. The bladder must also be able to contract to expel urine into the urethra. Tricyclic antidepressants can interfere with both processes and cause leakage, also called incontinence.
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In some people, a small amount of urine may leak from a sneeze. However, it may also be due to antihistamines taken to control allergy symptoms. The most common offenders are Benadryl (diphenhydramine) and Chlor-Trimeton (chlorpheniramine), says Jason Varin, PharmD, assistant professor at the University of Minnesota School of Pharmacy in Minneapolis. “The bladder is a smooth muscle that fills with urine. When it reaches a certain level and is full, it signals the brain that it’s time to urinate,” he explains. The problem is that certain antihistamines can relax the bladder, reducing the bladder’s ability to pass urine. Eventually, the bladder There is still some urine left, which means your bladder will refill faster and will send a signal to your brain “I need to pee” sooner.
The good thing about decongestants like Sudafed (pseudoephedrine) and Suphedrine PE (phenylephrine) is that they temporarily constrict blood vessels to relieve nasal congestion and ultimately reduce swelling. But the effects also occur in other muscles, including the bladder sphincter, says Dr. Varin. “This is the valve that opens and closes the bladder, and these drugs can constrict the bladder, making it more difficult for urine to leave the bladder,” he says. In men with male genitalia, “decongestants may constrict the prostate gland, which surrounds the urethra, making it difficult for urine to pass through,” adds Varin.
According to a previous study, 60% of older adults who visited a doctor for urinary incontinence were taking medications with urinary symptoms as a side effect. Among the most common medications they were taking? Calcium channel blockers. This class of medication used to treat high blood pressure can affect your bladder’s ability to relax and empty properly, says Hudspeth.
Lithobid (lithium) is a mood stabilizer used to treat bipolar disorder, notes the National Alliance on Mental Illness (NAMI). “For some people, lithium is the number one treatment that is considered a lifesaver, despite the many potential side effects,” says Varin. According to an article published in the International Journal of Bipolar Disorders in December 2016, one of these potential side effects is excessive urination and thirst, which can affect up to 70% of people taking lithium long-term. This side effect can be annoying, but it can also be dangerous if you take too many doses. “A lithium dose that is too high for an individual can cause kidney changes that affect kidney function and forms of diabetes,” explains Varin. This condition is called diabetes insipidus, which differs from type 1 or 2 diabetes. “Diabetes insipidus involves the ability of the kidneys to regulate body fluids and properly reabsorb water, resulting primarily in increased urination of body fluids. As a result, what is described as an insatiable thirst arises,” he says. Talk to your doctor if you have any of these side effects as they can cause electrolyte and fluid imbalances.
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Versacloz, FazaClo, and Clozaril (clozapine) are antipsychotic drugs that treat schizophrenia and may be especially important for people with suicidal thoughts, according to the US National Library of Medicine. Diabetes insipidus, says Hudspeth. One of the major complications of diabetes insipidus is dehydration, and symptoms include thirst, dry skin, fatigue, dizziness, confusion, and nausea, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). If you experience increased urination after taking this medication, talk to your doctor.
Newer drugs for type 2 diabetes, a class called SGLT2 (sodium-glucose cotransporter-2) inhibitors, are “liquid by increasing the amount of glucose, or sugar, in the blood that is excreted by the kidneys and passed through the urine.” says Varin. The good news: There have been concerns that SGLT2 inhibitors may also increase the risk of urinary tract infections (UTIs are a persistent urge to urinate, according to the Mayo Clinic), but more recent studies have not found a link. Clinical Kidney Journal February 2020 issue.
Alpha blockers, such as Cardura (doxazosin), Minipress (prazosin), and Hytrin (terazosin), are another class of drugs used to treat high blood pressure. They work by relaxing blood vessels to allow proper blood flow, but they can also cause urinary incontinence by relaxing the muscles in the urethra, says Hudspeth. According to the Mayo Clinic, these drugs are often used in combination with other blood pressure lowering medications, such as diuretics, so one or both medications may increase urination problems.
According to the Centers for Disease Control and Prevention (CDC), opioids are medications that doctors can prescribe to treat pain. They are highly addictive, and 1 in 4 people treated long-term with these drugs experience opioid addiction, according to the CDC. Obviously that’s the main concern. However, a minor side effect is urinary problems, according to a January 2017 article in the International Journal of Molecular Sciences. Opioids can affect your ability to empty your bladder by interfering with the bladder’s ability to contract properly. If side effects occur, your doctor may prescribe a different pain reliever.
Urine And Urination
If you have concerns about medications or urinary tract changes, see your primary care provider for medical evaluation and guidance. You will walk less and worry less both day and night.*
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